Key Publications

 

PLoS Pathogens

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Helicobacter pylori exploits a unique repertoire of type IV secretion system components for pilus assembly at the bacteria-host cell interface

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Shaffer CL, Gaddy JA, Loh JT, Johnson EM, Hill S, Hennig EE, McClain MS, McDonald WH, Cover TL

Cell Reports

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In vivo structures of the Helicobacter pylori cag type IV secretion system

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Chang YW*, Shaffer CL*, Rettberg LA, Ghosal D, Jensen GJ

 

mBio

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Peptidomimetic small molecules disrupt type IV secretion system activity in diverse bacterial pathogens

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Shaffer CL, Good JA, Kumar S, Krishnan KS, Gaddy JA, Loh JT, Chappell J, Almqvist F, Cover TL, Hadjifrangiskou M

 

Infection and Immunity

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Purine biosynthesis metabolically constrains intracellular survival of uropathogenic Escherichia coli

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Shaffer CL, Zhang EW, Dudley AG, Dixon BR, Guckes KR, Breland EJ, Floyd KA, Casella DP, Algood HM, Clayton DB, Hadjifrangiskou M

 

Full list of publications in PubMed